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Your healthcare professional can recommend ways to help you manage severe vomiting or diarrhea, as well as look for other potential causes

IGF-1 DES (Des(1-3) IGF-1) is a 67-amino acid truncated form of IGF-1 with the first three amino acids (Gly-Pro-Glu) removed from the N-terminus

It is a tripeptide composed of three amino acids cysteine, glutamic acid, and glycine

In a meta-regression analysis of 18 CVOTs, including 8 with GLP-1RAs, a significant association between HbA1c reduction and major adverse cardiovascular events (including cardiovascular mortality, non-fatal myocardial infarction [MI], heart failure, and non-fatal stroke) was shown

What's the Takeaway

GLP-1-based therapies downregulate proinflammatory responses in inflammatory related diseases