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In that situation, portal insulin levels are generally high due to insulin resistance [16,17]

Darwish et al., 2023)

SIN mainly controls ROS generation via the Nrf2-related signaling route and is crucial in the development of chronic inflammatory conditions like rheumatoid arthritis

Statements Author contributions MH: Data curation, Project administration, Methodology, Visualization, Software, Funding acquisition, Writing original draft, Formal analysis, Resources, Writing review & editing

Furthermore, it supports immune function by enhancing the activity of immune cells and modulating immune responses

Strong appetite suppression, better compliance in calorie deficits, and even potential benefits for body composition and motivation