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A missense variant in the GIPR, E354Qwhereby a glutamine (Q) at amino acid position 354 replaces a glutamic acid (E), identified in a genome-wide association study (GWAS), is linked with increased risk of T2D and higher BMI (Speliotes et al., 2010)

Neeland IJ, Jensen MD, Magkos F, et al

The Phase 2 trial enrolled 338 adults for 48 weeks

[Accessed 16th April 2026].

Research shows that a single exercise session, as well as long-term training, can enhance GLP-1 levels in the body for those who have type 2 diabetes, according to one review and meta-analysis

Your healthcare provider can assess whether dose reduction or switching to a different GLP-1 medication might be appropriate