We incorporated our genetic findings into broader models that combine demographic, clinical and genetic features to predict efficacy and side effects, and demonstrated the ability of this model to stratify patients by weight loss in a held out electronic health record (EHR) dataset
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The glucose-independent cardiovascular benefits of tirzepatide are currently being investigated in the SURPASSCVOT trial, a major ongoing study evaluating its cardiovascular risk profile
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Common side effects include nausea, vomiting, and constipationusually mild and transient but occasionally dose-limiting
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