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Nelson DB, Godoy MCB, Benveniste MF, Shewale JB, Spicer JD, Mitchell KG, Hofstetter WL, Mehran RJ, Rice DC, Sepesi B, Walsh GL, Vaporciyan AA, Swisher SG , Roth JA, Antonoff MB

Unwanted effects could be mild to severe, depending on the dosage

If a patient receives two different drugs by separate injection on the same date, two units may be billed, but modifier 59 (or XS for Medicare) is required on the second unit to prevent a duplicate-service denial

Side effects can include injection site reactions (pain, swelling, redness), headache, flushing, dizziness, and nausea

In the U.S., state medical boards could similarly sanction physicians for gross deviations from standard care if a complaint is filed

Biswas S, Zhao X, Mone AP, Mo X, Vargo M, Jarjoura D, et al