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Given that species-specific differences have been reported for other multi-agonists such as tirzepatide [35], further studies using human islets are warranted to confirm the involvement of GLP-1R and the GqTRPM5 signalling axis in humans

The mature cochlear receptor cells, the inner and outer hair cells (HCs), as well as the cochlear neurons do not regenerate, making any cellular loss permanent

Ricci, A., Caiati, C., Galantino, A., Scrutinio, D., Valentini, G., Chiddo, A., and Rizzon, P