Huang TH, Lin CF, Alalaiwe A, Yang SC, Fang JY
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This study suggests that GLP-1RAs could be promising new therapeutic agents for obese asthma patients, particularly due to their impact on the expression of IL-1 modulated by nucleotide oligomerization domain-like receptor protein 3 (NLRP3) [249]
Mice expressing this receptor and treated with the specific GiD activator clozapine N -oxide (CNO) displayed an impaired glucose tolerance associated with a lack of GSIS in vivo [42]