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Research suggests tirzepatide may lead to greater average weight loss than semaglutide for some adults with obesity or overweight

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Mayatepek E, Hoffmann GF, Larsson A, Becker K, Bremer HJ: 5-Oxoprolinase deficiency associated with severe psychomotor developmental delay, failure to thrive, microcephaly and microcytic anaemia

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There is no set date to stop the medication, but in the clinical trials studying these treatments, the medications were taken for 1 year