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The activation of GLP-1R is associated with glucose-induced insulin secretion and inhibition of -cell glucagon release [43]

Adding semaglutide or tirzepatide adds redundant GLP-1 (and GIP, in the case of tirzepatide) activity without new pathway coverage

Medication comes from independent licensed pharmacies

How Genetic Testing Personalizes Affordable GLP-1 Treatment The PlexusDx Precision Peptide Genetic Test ($99 add-on after your first month) analyzes GLP1R (rs6923761), GIPR (rs1800437), FTO (rs9939609), and MC4R (rs17782313) variants that relate to GLP-1 and related signaling pathways

C., Flint, A., Jacobsen, J

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