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In animal models of atherosclerosis, the GLP1 analogue exendin 4 substantially reduced the accumulation of monocytes and macrophages in the vascular wall and inhibited atherogenesis by regulating inflammation in macrophages 95

GLP-1 was originally identified as a 37 amino acid (GLP-1 137 ) long peptide

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Figure 2 Although data from literature indicate that GLP-1 inhibits ANG II action, its effect on aldosterone is less established