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While allergic reactions to tirzepatide are uncommon, certain patient characteristics and clinical factors may increase susceptibility

Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology, 131 (5), 645

The dual mechanism produces greater appetite suppression and metabolic effects than GLP-1 agonism alone, which explains the superior weight loss results

2002;51:S434S442