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Set to the tune of Childish Gambino's "This Is America," the 60-second spot, which reportedly cost between $14 million and $16 million to air during the big game, is plugging "affordable" versions of these medications, known as compounded GLP-1s (short for "glucagon-like peptide-1")

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Common type II RET inhibitors against RET -positive cancers include cabozantinib, sorafenib, ponatinib etc., all of which show good efficacy ( Figure 2 )