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These findings align with a model in which ERR activation restores mitochondrial oxidative capacity and lipid flux in hepatocytes, contributing to reversal of steatotic features

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A pivotal point early on in this research was the use of the known peptide sequence of glucagon to facilitate the discovery of other glucagon-like peptides in the gastrointestinal tract with the help of the radioimmunoassay method (6, 7)