Found in the pituitary gland in vertebrates including humans, -MSH is a melanocortin receptor agonist that contributes to several physiological processes, including melanogenesis, appetite modulation, and sexual desire
doi:10.1146/annurev.nutr.21.1.381
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The question isn't whether levels decline it's whether yours have declined enough to cause symptoms
Efficiency of various bile salt preparations for stimulation of Clostridium difficile spore germination
