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There is only 1 previous report of the appearance of large erythematous edematous plaques in the areas of injection of lipolytic substances, similar to those observed in our patient.10 The injection of excessive quantities of substances with a lipolytic effect, poor circulation, previous scarring in the area treated, or a poor injection technique that leaves the bolus too superficial, are possible causes of the appearance of this complication

[DOI] [PubMed] [Google Scholar] Johnson T

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Most peptide-based protocols have an adaptation curve, and tirzepatide is no exception

These benefits arise from the phospholipid bilayer of liposomes acting as a protective barrier and absorption aid the bilayer isolates the active compound from degradative factors (oxygen, low pH) and can fuse with biological membranes to facilitate uptake

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