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Anemia can also be caused by a restricted diet, poor iron absorption, repeated blood testing, or the hemodialysis removal of iron and vitamins

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Nonheme iron requires gastric acid for conversion to the ferrous form of iron for absorption.[196] 90% of dietary and 100% of oral iron supple-mentation is in the nonheme form.[197] So not surprisingly, several review studies in the literature conclude that PPI use leads to decreased iron absorption.[198,199] In one study, all markers of iron deficiency were decreased among patients on PPI therapy as compared to controls

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