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It has been demonstrated that GSH depleted astrocytes lose their neuroprotective roles, leading to neuronal toxicity and a consequent reduction in cell viability (Pizzurro et al., 2014a,b)

Moreover, the levels of proteins associated with cell proliferation, migration, and angiogenesis (Slc38a2, Psph, Jagn1, and Rorb) were upregulated

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Targeted LC-MS/MS is described in the literature as a major analytical method for peptide and protein identification or quantification in research settings, with strengths that include specificity and reproducibility [11]

However, appropriate use extends beyond FDA label indications

The activity of glucokinase in -cells is controlled by its subcellular localization