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Vitamin D deficiency is common, in part because people who are sick tend to stay at home and not get enough sunshine

Enzyme selectivity for cleavage immediately C-terminal to proline or alanine residues at position 2 substrate peptides is dictated by the shape and size of the S1 pocket, which is lined by Val656, Tyr631, Tyr662, Trp659, Tyr666, and Val711 (Figure 6)

SREBP1, sterol regulatory elementbinding protein 1

This ambiguity makes them incredibly versatile, perfect for creating ethereal and dreamy soundscapes, moments of suspense, or gentle, floating textures

doi: 10.1371/journal.ppat.1000383

There is also the slight risk of nerve injury with IM shots