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Thus, as the SLC1A5 variant is the only currently known glutamine transporter in the mitochondrial inner membrane 16 , targeting the SLC1A5 variant could be an effective strategy for selectively inhibiting glutamine metabolism in cancer cells (Fig

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Symptoms and outcomes can include: Recurrent miscarriage Difficulty conceiving Neural tube defects (spina bifida, cleft lip/palate) Down syndrome Preeclampsia and pregnancy hypertension If youre planning pregnancy, supporting methylation and folate pathways is critical