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Consistent with these reports, previous lineage tracing of Nestin + MSCs in vivo revealed a relatively quiescent state in adult mice as minimal GFP positive cells could be identified one month after induction, whereas abundant GFP expression was detected 8 months after induction (27)

MOTs-C A peptide derived from mitochondrial DNA

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In the context of lean mass preservation, future research should integrate more precise and clinically meaningful measures of muscle health, including muscle composition, mobility, and strength, rather than relying solely on body composition changes

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