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IL-8: P = 0.0002), while IL-10 decreased from day 0 to 56 ( P = 0.03

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Depending on the severity of the symptoms, a hangover can be mild (with a slight headache and fatigue or just general discomfort), moderate (moderate-to-severe headache, nausea, vomiting, irritability, fatigue, and dehydration),or severe (intense and severe headache, mood swings, anxiety, dizziness, severe nausea and vomiting, impaired concentration, muscle pain, extreme weakness, and fatigue)