Regardless of their origin, they function as similar enough 'keys' to unlock those GLP-1 receptor 'locks' and flip them on
C.TrappS.et al (2014)
Specifically, first-year discontinuation rates are about 45% for patients with T2DM and 65% for those without (Rodriguez et al., 2025)
The truth is that microdosing tends to be gentler on metabolism, which makes it easier to maintain muscle
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Higher doses produce more total weight loss, but the proportion of that weight loss coming from fat versus lean tissue varies with dose, activity level, and protein intake during the protocol