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Milk thistle is the plant (Silybum marianum), whilst silymarin is the standardised extract derived from its seeds, containing a mixture of flavonolignans with silybin as the main active component

[PMC free article: PMC425362] [PubMed: 6389599] 34

This may be attributed to the dimeric structure which hinders enzyme access to active sites, showcasing significant resistance to enzymatic degradation 49,55

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