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Final Thoughts The growth-hormone secretagogue class isn't one thing it's at least two distinct mechanisms (GHRH analogs and GHS/ghrelin agonists) that researchers study both individually and, increasingly, in combination

Wegovy contains the active ingredient semaglutide, and is prescribed for adults with obesity

Ethics statement The animal study was approved by Institutional Animal Care and Use Committee at the Child Health Institute, Rutgers University, New Brunswick, NJ

Long-term clinical trials, spanning several years, are underway to assess the durability of weight loss, as well as the potential for any delayed or rare side effects

Not all semaglutide is created equal

10.1136/jitc-2020-001369 55 ElshazliR