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Users who lost 20 percent on the medication typically retained only 7 to 8 percent of the loss at 12 months off

increased risk of low blood sugar (hypoglycemia) in patients with type 2 diabetes, especially those who also take medicines for type 2 diabetes such as sulfonylureas or insulin

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Hypoglycaemia (low blood sugar) is uncommon with GLP-1 receptor agonist monotherapy in people without diabetes