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A selective non-competitive inhibitor of VMAT2 VMAT1 is a different isoform expressed in peripheral neuroendocrine cells (adrenal chromaffin cells, interneurons of sympathetic ganglia, and enterochromaffin cells that store serotonin in the GI tract)

The study involved zebrafish larvae at four days post-fertilization (4 dpf)

Which substances and methods are prohibited

Treatment with rosmarinic acid prevented the observed changes in the A group and in another study attenuated A staining and astrocyte activation and enhanced auditory abilities (Kantar Gok et al., 2018)

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One key player in this response is posited to be MST1, a protein that increases its activity in the presence of oxidative stress