allodynia from glp 1 is being reported with GLP-1 medications It is a heightened sensitivity to touch that can feel like pain. We are seeing it more at higher doses The important point is that Allodynia is being reported with

doi:10.1038/srep19076

3 Although several factors contributed to this rise in interest, two key developments have been particularly important: Celebrity endorsement: A number of high-profile celebrities, such as Elon Musk, have publicly credited GLP-1RA drugs with their transformative weight loss, leading to a spike in public interest in using the drugs for weight loss

The description of the chi-square test in shown in the Multimedia Appendix 4

[DOI] [PubMed] [Google Scholar] 45.Zhang Q, Delessa CT, Augustin R, Bakhti M, Collden G, Drucker DJ, et al

Its levels decline significantly with age, which is one reason it has become a focal point for regenerative medicine and cosmetic science

L-carnitine accomplishes this by binding to acyl residues produced not only from fatty acids but also from amino acid metabolism, forming water-soluble acylcarnitines that facilitate their excretion from cells and ultimately the body (Figure 1) ( 2.4 Stabilization of cell membranes L-carnitine is also essential in maintaining membrane stability and the function of plasma, mitochondria, and other organelles, probably through its effects on the acetylation of membrane phospholipids