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Highlights Ubx homodimerization enables decoupling of DNA- and RNA-dependent splicing regulation The homeodomain K58 amino acid is critical for Ubx-RNA binding ability Ubx-RNA binding ability is essential for splicing regulation Dual DNA/RNA binding activities shape Ubx homeotic functions INTRODUCTION Transcription factors (TFs) play a critical role in coordinating the development of multicellular organisms by regulating precise gene expression programs 1,2
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In turn, lack of OXPHOS results in accumulation of reducing compounds in and outside the mitochondrial matrix, a condition known as reductive stress 310
Natural Sulforaphane From Broccoli Seeds Against Influenza A Virus Replication in MDCK Cells