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The enzymatic activity of prolyl 4-hydroxylase subunit alpha 1 (P4HA1), a procollagen-proline, 2-oxoglutarate 4-dioxygenase, is crucial for collagen polypeptide chain folding into stable triple-helical molecules and consequently for ECM deposition [23]

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Patients taking Mounjaro who require hospitalisation or surgery should inform their healthcare team about their medication, as temporary adjustments may be necessary according to local anaesthesia and surgical policies

doi: 10.1126/sciimmunol.aar6676 [DOI] [PubMed] [Google Scholar] 286.Hernandez-Velazquez ED, Alba-Betancourt C, Alonso-Castro AJ, et al

GLP-1RAs may also have a direct impact by reducing the levels of beta-amyloid and tau hyperphosphorylation in Alzheimers disease [76]

And the answer is: yes, and no