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COG/KOG annotation is most effective for microbial functional profiling, comparative genomics, and evolutionary studies, and forms a valuable component of multi-omics annotation pipelines that combine multiple knowledgebases for deeper biological insight

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Bohn B, Herbst A, Pfeifer M et al (2015) Impact of physical activity on glycemic control and prevalence of cardiovascular risk factors in adults with type 1 diabetes: a cross-sectional multicenter study of 18,028 patients

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