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Despite being derived from angiotensin IV (a true peptide), Dihexa's chemical structure has been extensively modified: it incorporates non-natural amino acid analogs and a hexanoic acid cap that make it structurally distinct from conventional peptides

Pellegrini A, Hgeli G, von Fellenberg R: Isolation and characterization of two new low-molecular-weight protein proteinase inhibitors from the granule-rich fraction of equine neutrophilic granulocytes

Credit: Arthrex.com For certain patients, typically those that have previously had most of their meniscus removed, a meniscus transplant can also be performed

Frequency: Use once or twice daily for optimal results

Singh et al., 2018)