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After filtering to retain participants with information regarding pre-treatment and post-treatment BMI and genotype data passing quality control, we obtained 4,889 participants, of which 3,948 had complete data when incorporating covariates akin to those used in the GWAS
To define the molecular basis of the metabolic dysfunction caused by CI loss in adipocytes, we next analysed the transcriptome in visceral WAT
Opioids Opioids mask pain through central nervous system effects but carry risks of tolerance, dependence, overdose, and paradoxical opioid-induced hyperalgesia
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The concurrent use of these medications requires careful clinical consideration for several important reasons
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