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Liposomes are capable of encapsulating both hydrophobic and hydrophilic drugs and also have the potential of fusion with the cell membrane to modulate its fluidity and facilitate the skin penetration and distribution of the loaded drug (Sharma et al., 2018)

(90) suggested that an optimal total length of the alimentary limb should be around 300 centimeters to minimize the risk of malnutrition and reduce the occurrence of diarrhea, thereby improving the overall quality of life for patients undergoing these complex conversional procedures

However, there were no significant differences in HbA1c reductions between any of the cotadutide dose groups and the liraglutide (1.8 mg) group