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It is important to note that these data were obtained using a surrogate molecule and may not be directly extrapolated to the clinical candidate, Maridebart Cafraglutide (MariTide)

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This process requires a significant amount of energy and produces its own metabolic byproducts

The post says an eGFR assessment is recommended before initiation, especially in older adults or people with diabetes, and it notes that both medications can influence fluid balance and renal perfusion