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In a study conducted on Japanese patients with T2DM, those who received tirzepatide doses ranging from 5 to 15 mg for 52 weeks experienced a significant decrease in HbA1c levels by 2.43.02%

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Through a combined application of transcriptomics, proteomics, and metabolomics, we observed PGC-1 overexpression in MBCCs and demonstrated that PGC-1 silencing inhibits cancer cell energy metabolism and metastatic potential

Wen X, Li T, Xu X