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Glucose-dependent insulinotropic polypeptide analogues and their therapeutic potential for the treatment of obesity-diabetes

Endocrinology 133: 57-62, 1993

*In a study of 3,250 WW Clinic patients, patients that were prescribed a GLP-1 lost on average 21% of their body weight at 12 months

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examined long- and short-term CR in femora and vertebrae, demonstrating that the initially deleterious impact of CR on cancellous bone diminishes with age

However, none of the above studies investigated whether bone biomechanic and resistance to fracture were improved following administration of GLP-1Ra