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* Charlotte Mishbach, et al., Echocardiography and conventional Doppler examination in clinically healthy adult Cavalier King Charles Spaniels: Effect of body weight, age, and gender, and establishment of reference intervals

doi: 10.1080/15321819.2019.1583109 150 ChandrashekaranVSethRKDattaroyDAlhassonFZiolenkaJCarsonJet al

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Although the previous school of thought centers around cGMP pathways, calcium handling, and antioxidant capacity, new evidence illuminates excitationcontraction coupling and myofilament function as primary mechanisms modulating contractile function