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Any potential transdiagnostic benefit of GLP-1RAs may be amplified by their established effects on cardiovascular and metabolic morbidity and mortality 21,22 , which are known to be raised in several cognitive and mental health disorders 244,245

DAmour KA, Bang AG, Eliazer S, Kelly OG, Agulnick AD, Smart NG, et al (2006) Production of pancreatic hormoneexpressing endocrine cells from human embryonic stem cells

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The biomarker clusters with increased lactate, pyruvate, alanine, and sometimes tricarboxylic acid cycle (TCA) intermediates (Figure 5, group 1), suggest dysfunction of oxidative phosphorylation or the TCA cycle

Hyperoxia exposure impairs mitochondrial respiratory capacity in premature lung endothelial cells, ultimately triggering apoptosis