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In a rat model of arthritis, synovial pannus cells increase glucose uptake 42 , and HK2, a rate-limiting enzyme of glycolysis, regulates the aggressive functions of FLS 21

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Semaglutide is contraindicated in individuals with a personal or family history of medullary thyroid carcinoma or multiple endocrine neoplasia type 2 due to preclinical findings of C-cell tumors in rodents[13]

Bordon, K