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and delaying gastric emptying

A compelling area for future research is to investigate whether GLP-1-RAs modulate taste perception in part by altering the expression or signaling of leptin or cholecystokinin (CCK) in taste bud cells, creating an integrated hormonal milieu that fine-tunes taste sensitivity based on energy status

Prescribers typically review estimated glomerular filtration rate, or eGFR, before starting and during treatment

239,240 In summary, GLP-1 lowers blood glucose levels and inhibits glucagon secretion through direct action on -cells, promotion of insulin secretion, and regulation of gastrointestinal activity

While weight regain isnt a side effect, it is a possible issue when stopping GLP-1 medication abruptly once theyve reached their goals

Take home message Weight-loss injections are designed as additional tools for weight management interventions and shouldnt be considered lifelong medications