Additionally, because Ipamorelin is a selective growth hormone secretagogue, it does not increase plasma levels of cortisol, the stress hormone, or adrenocorticotropic, another hormone originating in the pituitary gland
Excessive muscle loss can reduce metabolic rate, potentially making weight maintenance more challenging, and may impair physical function, particularly in older adults or those with limited muscle reserves at baseline
Growth factors play a major role in initiating the angiogenesis process and several drugs act on these specific growth factors directly or indirectly which can be repurposed to activate angiogenesis and accelerate the healing of different types of wounds (burns, diabetic ulcers, and trauma wounds)
Skeletal muscles switch to fatty acid oxidation when they are in use, such as lifting weights, aerobics, sports, etc, but when at rest, they have a low rate of fatty acid oxidation
The benefit is greater in moderate HIE (Edwards et al, 2010)