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You may experience nausea or vomiting and may require medical treatment

In those with T2D, GLP-1RAs reduced the composite kidney outcome by 18% compared with placebo (HR 0.82

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Propionyl-L-carnitine in intermittent claudication: double-blind, placebo-controlled, dose titration, multicenter study

That hormone prompts the pancreas to release insulin when blood sugar is high, slows how fast the stomach empties, and helps bring blood sugar down

A 2025 review on skeletal muscle health noted that clinical trials of incretin-based therapies suggest proportional loss of fat and lean mass during weight loss, while preclinical and translational work hints that the picture may be more complex than a purely muscle-wasting effect