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2 febbraio 2024;17(2):199 Allison KC, Chao AM, Bruzas MB, McCuen-Wurst C, Jones E, McAllister C, et al

User-reported experiences with extended Wegovy dosing 10-11 day spacing: Some users report manageable results with minimal hunger return 14-day (biweekly) spacing: Most report significant hunger return and reduced effectiveness Appetite control: Generally good for the first 7-8 days, diminishing noticeably afterwards Side effects: More variable and less predictable than with weekly dosing Weight loss: Typically slower than with weekly dosing Overall sentiment: Financially appealing, but less effective Safe alternatives to consider instead of extended dosing Rather than adapting medication schedules without clinical guidance, consider these evidence-based alternatives: 1

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Growth hormone and IGF-1 are involved in muscle protein synthesis, fat oxidation, and tissue repair, so it is reasonable that restoring more youthful GH signaling could influence those areas