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This is the most common pattern in dermatology editorial guidance

If no improvement appears after six months of consistent use, consider whether the protocol needs modification

In rare cases, allergic reactions like itching or rash may occur

Route: The injection is typically given intramuscularly (IM) into a large muscle, such as the thigh or buttock, or subcutaneously (SC) into the subcutaneous tissue

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These concerns can have many causes, so provider evaluation is important