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[11] [12] For weight management, NICE (TA875, TA664) recommends these medications for adults with a BMI of 35 kg/m or more (or 32.5 kg/m or more for people from South Asian, Chinese, other Asian, Middle Eastern, Black African or African-Caribbean family backgrounds) who have at least one weight-related comorbidity and are receiving care through specialist weight management services

The initial phase typically involves 2-5 pounds of loss, partly from reduced caloric intake and partly from fluid shifts as your metabolism adjusts

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Over time (typically between 3-6 months), more dramatic changes, including increased lean muscle mass, decreased body fat, and increased natural growth hormone (HGH) levels, will occur

Retrieved 27 October 2019

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