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Both medications increase gastrointestinal side effects when combined, and they can interact through insulin and growth hormone pathways

The inflammatory responses induced during reperfusion are crucial to the development of I/R injury and associated consequences, including bloodbrain barrier (BBB) impairment and cognitive dysfunction (Venkat et al., 2017)

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To investigate this, we introduced a mutation where cys115 was replaced with alanine, resulting in the inhibition of H 2 S-induced sulfhydration of Syvn1 in HL-1 cardiomyocytes (Fig