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TBARS were lower by 23% on day 42 in VC + VE compared to Controls (Table 1)
Donepezil, an acetylcholinesterase inhibitor, has shown promising results in mitigating cardiotoxicity induced by chemotherapeutic agents like doxorubicin and trastuzumab
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Melanocytes in the human body are localized in the skin, iris, ciliary body, choroid, retina, and adrenal medulla, and in the CNSin the pia mater and substantia nigra [2]
One important unresolved issue is the limited evidence regarding concomitant use of SGLT2 inhibitors and GLP-1 receptor agonists, a gap also acknowledged in European Society of Cardiology guidelines and Current guidelines prioritize SGLT2 inhibitors in patients with T2DM who have HF, chronic kidney disease, or elevated cardiovascular risk, while GLP-1 receptor agonists are emphasized for patients with obesity or established atherosclerotic cardiovascular disease [7]
