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Yet putting patients into a hyperthyroid state has consequences--often producing dangerous increases in heart rate, body temperature and blood pressure

Licensed clinicians determine whether prescribing may proceed and which medication category is appropriate

MK-677 increases fasting blood glucose and insulin levels

If side effects or cost are forcing poor adherence, talk to your provider about stepping strategies that preserve benefit while lowering expense, such as trialing lower doses, switching to an alternate GLP1 with better coverage for your diagnosis, or trying other approved therapies first

Circulation, 146(24), 18821894

Several others preceded it, and newer molecules have followed