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Elevated levels of proinflammatory cytokines (Khaibullin et al., 2017) and increased levels of chemokines responsible for recruiting peripheral immune cells and activating the adaptive immune response (Kalinowska-yszczarz et al., 2011), have been found in MS patients

The brain can respond by increasing muscle tone to protect the area, which further restricts blood flow and maintains the knot

Furthermore, other redox-maintaining enzymes such as glutathione peroxidases, and detoxification enzymes, glyoxylases, are closely related to carbohydrate metabolism [15,16]

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