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The databases used were PubMed, maintained by the US National Library of Medicine at the National Institutes of Health, Science Direct and Scopus by Elsevier, and Google Scholar (retrieved from 1 June to 26 August 2025)

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Accordingly, some features of the mentioned models give rise to differences on timely physiological deviations between models, particularly if the focus is turned onto earlier time points of the disease progression

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